What is the Medetomidine?

Medetomidine is , while it's Molecular Formula is C13H16N2. Medetomidine is used in method for synthesizing Medetomidine using 2,3-Dimethylphenylmagnesium Bromide.

What is the CAS number for Medetomidine?

The CAS number of Medetomidine is 86347-14-0.

What is Medetomidine (86347-14-0) used for?

Medetomidine is a synthetic compound used as a surgical anesthetic and analgesic. It is normally found as its hydrochloride salt, medetomidine hydrochloride. Medetomidine is an intravenously available alpha-2 adrenergic agonist. The drug has been developed by Orion Pharma. In the United States, it is currently approved for its veterinary use in dogs and distributed by Pfizer Animal Health. In Canada, medetomidine is distributed by Novartis Animal Health. The marketed product is a racemic mixture of two stereoisomers from which dexmedetomidine is the main active isomer.InChI:InChI=1/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)

What is the (R)-4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole hydrochloride?

(R)-4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole hydrochloride is White or off white crystalline powder, while it's Molecular Formula is C13H16N2 . HCl. White or off white crystalline powder α2-Adrenergic agonist. Sedative; analgesic.

What is the CAS number for (R)-4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole hydrochloride?

The CAS number of (R)-4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole hydrochloride is 86347-15-1.

What is (R)-4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole hydrochloride (86347-15-1) used for?

(R)-4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole hydrochloride is a chiral compound characterized by its specific stereochemistry, with the R-configuration at the 4-position of the imidazole ring. It features a 2,3-dimethylphenylethyl group attached to the imidazole core, and the presence of hydrochloride indicates that it is a salt form, which can enhance its solubility and stability in certain conditions. (R)-4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole hydrochloride is a white solid, which is a common characteristic for many organic compounds, facilitating its handling and formulation in various applications.InChI:InChI=1/C13H16N2.ClH/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13;/h4-8,11H,1-3H3,(H,14,15);1H

Medetomidine HCl

Basic information

Product Name:Medetomidine HCl
CasNo.:86347-15-1
MF:C₁₃H₁₆N₂^.HCl
MW:236.744

Physical and Chemical Properties

Purity:99%
Boiling Point:164-166°C
Packing:White or off white crystalline powder
Throughput:

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Product Details

CasNo： 86347-15-1

MF： C₁₃H₁₆N₂^.HCl

Appearance： White or off white crystalline powder

Trustworthy Manufacturer Supply 86347-15-1 with Efficient Delivery, Factory Sells Medetomidine HCl

Molecular Formula:C13H16N2^.HCl
Molecular Weight:236.744
Appearance/Colour:White or off white crystalline powder
Vapor Pressure:1.08E-05mmHg at 25°C
Melting Point:164-166°C
Boiling Point:381.9 °C at 760 mmHg
Flash Point:191.3 °C
PSA：28.68000
LogP:3.98030

Medetomidine HCl(Cas 86347-15-1) Usage

Description	Medetomidine hydrochlorideProduct ingredient for Medetomidine. Medetomidine is a synthetic compound used as a surgical anesthetic and analgesic. It is normally found as its hydrochloride salt, medetomidine hydrochloride. Medetomidine is an intravenously available alpha-2 adrenergic agonist.
Biological Activity	medetomidine is a selective α2-adrenoceptor agonist, with ki of 1.08 nm, exhibts 1620-fold selectivity over α1-adrenoceptor.

InChI:InChI=1/C13H16N2.ClH/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13;/h4-8,11H,1-3H3,(H,14,15);1H

86347-15-1 Relevant articles

Sedative and cardiopulmonary effects of medetomidine hydrochloride and xylazine hydrochloride and their reversal with atipamezole hydrochloride in calves

Eva Rioja DVM, PhD, Carolyn L. Kerr DVM, DVSc, PhD, Saad S. Enouri BVSC, MSC, and Wayne N. McDon

American Journal of Veterinary Research, Volume/Issue: Volume 69: Issue 3

A 2-phase (7-day interval) study was performed. Sedative characteristics (phase I) and cardiopulmonary effects (phase II) of medetomidine hydrochloride and xylazine hydrochloride administration followed by atipamezole hydrochloride administration were evaluated. In both phases, calves were randomly allocated to receive 1 of 4 treatments IV: medetomidine (0.03 mg/kg) followed by atipamezole (0.1 mg/kg; n = 6), xylazine (0.3 mg/kg) followed by atipamezole (0.04 mg/kg; 7), medetomidine (0.03 mg/kg) followed by saline (0.9% NaCl; 6) solution (10 mL), and xylazine (0.3 mg/kg) followed by saline solution (10 mL; 6). Atipamezole or saline solution was administered 20 minutes after the first injection.

Cardiopulmonary evaluation of the use of medetomidine hydrochloride in cats

Leigh A. Lamont DVM, Barret J. Bulmer DVM, Kurt A. Grimm DVM, MS, William J. Tranquilli DVM, MS

American Journal of Veterinary Research, Volume/Issue: Volume 62: Issue 11

To evaluate the cardiovascular effects of the α2-adrenergic receptor agonist medetomidine hydrochloride in clinically normal cats. Heart rate, cardiac index, stroke index, ratepressure product, and right and left ventricular stroke work index significantly decreased from baseline after medetomidine administration, whereas systemic vascular resistance and central venous pressure increased. However, systolic, mean, and diastolic arterial pressures as well as arterial pH, and oxygen and carbon dioxide tensions were not significantly different from baseline values.

86347-15-1 Upstream products

1021949-47-2
1-(4-imidazolyl)-1-(2,3-dimethylphenyl)ethylene
86347-14-0
medetomidine
1421259-21-3
2-bromo-3-(2,3-dimethylphenyl)butanal
3473-63-0
formamidine acetic acid

86347-15-1 Downstream products

86347-14-0
medetomidine
145108-58-3
(+)-(S)-4-(1-[2,3-dimethylphenyl]ethyl)-1H-imidazole hydrochloride

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