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CasNo: 895152-66-6
MF: C16H19NO
In chemical synthesis, (1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone is often used as a key intermediate in the synthesis of other complex molecules. Through it, compounds with specific functions and properties can be further synthesized to meet the needs of medicine, pesticides, materials science and other fields.
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Synthetic cannabinoids are a group of co...
A series of potent indol-3-yl-tetramethy...
indole
2,2,3,3-tetramethylcyclopropanecarbonyl chloride
(1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone
Conditions | Yield |
---|---|
indole; With zirconium(IV) chloride; In dichloromethane; at 0 ℃; for 0.0833333h; Inert atmosphere;
2,2,3,3-tetramethylcyclopropanecarbonyl chloride; In dichloromethane; at 0 ℃; for 4h; Inert atmosphere;
|
85% |
2,2,3,3-tetramethylcyclopropanecarbonyl chloride
1-[(2,2,3,3-tetramethylcyclopropyl)carbonyl]-1H-indole
(1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone
Conditions | Yield |
---|---|
indole; With ethylmagnesium bromide; In tetrahydrofuran; dichloromethane; at 20 ℃; for 0.25h;
With zinc(II) chloride; In tetrahydrofuran; dichloromethane; at 20 ℃; for 0.5h;
2,2,3,3-tetramethylcyclopropanecarbonyl chloride; In tetrahydrofuran; dichloromethane; at 20 ℃; for 6h;
|
42% 27% |
2,2,3,3-tetramethylcyclopropanecarbonyl chloride
indole
2,2,3,3-tetramethylcyclopropane-1-carboxylic acid
(1-butyl-1H-indol-3-yl)-(2,2,3,3-tetramethylcyclopropyl)methanone
(2,2,3,3-tetramethylcyclopropyl)[1-(4,4,4-trifluorobutyl)-1H-indol-3-yl]methanone
(1-pentyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone
(1-propyl-1H-indole-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone