(1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone

Basic information

  • Product Name:(1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone
  • CasNo.:895152-66-6
  • MF:C16H19NO
  • MW:241.333

Physical and Chemical Properties

  • Purity:99%
  • Boiling Point:
  • Packing:
  • Throughput:
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Product Details

CasNo: 895152-66-6

MF: C16H19NO

Chinese Manufacturer Supply Top Purity 895152-66-6 (1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone with Competitive Price

  • Molecular Formula:C16H19NO
  • Molecular Weight:241.333
  • Boiling Point:375.009 °C at 760 mmHg 
  • PKA:15.50±0.30(Predicted) 
  • Flash Point:188.03 °C 
  • PSA:32.86000 
  • Density:1.099 g/cm3 
  • LogP:4.03280 

895152-66-6 (1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone Usage

In chemical synthesis, (1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone is often used as a key intermediate in the synthesis of other complex molecules. Through it, compounds with specific functions and properties can be further synthesized to meet the needs of medicine, pesticides, materials science and other fields.

Dorne chemical technology co. LTD is a comprehensive chemical enterprise integrating r&d, production and sales. It is a leading manufacturer and supplier of chemical products in China.We develop, produce and market high quality pharmaceuticals, intermediates, specialty chemicals and OLED intermediates, as well as other fine chemicals.Relying on the laboratory and taking the factory as the base, the company has the whole process ability of fine chemical product research and development, production and processing, testing and packaging to export.We have a research team of excellent engineers, professional technical personnel dedicated to the research and development of new products,

895152-66-6 Relevant articles

Concise Synthesis of Potential 4-Hydroxy-5-fluoropentyl Side-Chain Metabolites of Four Synthetic Cannabinoids

Dahlén, Johan,Konradsson, Peter,Liu, Huiling,Rexander, Anders,Vestling, Erik,Wallgren, Jakob,Wu, Xiongyu

supporting information, p. 517 - 520 (2020/03/13)

Synthetic cannabinoids are a group of co...

Indol-3-yl-tetramethylcyclopropyl ketones: Effects of indole ring substitution on CB2 cannabinoid receptor activity

Frost, Jennifer M.,Dart, Michael J.,Tietje, Karin R.,Garrison, Tiffany R.,Grayson, George K.,Daza, Anthony V.,El-Kouhen, Odile F.,Miller, Loan N.,Li, Lanlan,Yao, Betty B.,Hsieh, Gin C.,Pai, Madhavi,Zhu, Chang Z.,Chandran, Prasant,Meyer, Michael D.

, p. 1904 - 1912 (2008/09/21)

A series of potent indol-3-yl-tetramethy...

895152-66-6 Process route

indole
120-72-9

indole

2,2,3,3-tetramethylcyclopropanecarbonyl chloride
24303-61-5

2,2,3,3-tetramethylcyclopropanecarbonyl chloride

(1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone
895152-66-6

(1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone

Conditions
Conditions Yield
indole; With zirconium(IV) chloride; In dichloromethane; at 0 ℃; for 0.0833333h; Inert atmosphere;
2,2,3,3-tetramethylcyclopropanecarbonyl chloride; In dichloromethane; at 0 ℃; for 4h; Inert atmosphere;
85%
2,2,3,3-tetramethylcyclopropanecarbonyl chloride
24303-61-5

2,2,3,3-tetramethylcyclopropanecarbonyl chloride

1-[(2,2,3,3-tetramethylcyclopropyl)carbonyl]-1H-indole
895157-31-0

1-[(2,2,3,3-tetramethylcyclopropyl)carbonyl]-1H-indole

(1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone
895152-66-6

(1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone

Conditions
Conditions Yield
indole; With ethylmagnesium bromide; In tetrahydrofuran; dichloromethane; at 20 ℃; for 0.25h;
With zinc(II) chloride; In tetrahydrofuran; dichloromethane; at 20 ℃; for 0.5h;
2,2,3,3-tetramethylcyclopropanecarbonyl chloride; In tetrahydrofuran; dichloromethane; at 20 ℃; for 6h;
42%
27%

895152-66-6 Upstream products

  • 24303-61-5
    24303-61-5

    2,2,3,3-tetramethylcyclopropanecarbonyl chloride

  • 120-72-9
    120-72-9

    indole

  • 15641-58-4
    15641-58-4

    2,2,3,3-tetramethylcyclopropane-1-carboxylic acid

895152-66-6 Downstream products

  • 1199943-43-5
    1199943-43-5

    (1-butyl-1H-indol-3-yl)-(2,2,3,3-tetramethylcyclopropyl)methanone

  • 895155-78-9
    895155-78-9

    (2,2,3,3-tetramethylcyclopropyl)[1-(4,4,4-trifluorobutyl)-1H-indol-3-yl]methanone

  • 1199943-44-6
    1199943-44-6

    (1-pentyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone

  • 1199943-42-4
    1199943-42-4

    (1-propyl-1H-indole-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone